Primrose plus contains evening primrose oil which is a rich source of essential fatty acids which are essential for the maintenance of good health. primrose plus replenish essential fatty acids which are diminished in variety of symptoms and diseases including premenstrual syndrome, mastalgia, rheumatoid arthritis and atopic dermatitis.pharmacological action: evening primrose oil in primrose plus is a unique supplement of linoleic acid & substantial amounts of gammalinolenic acid (gla). gla is the precursor of the prostaglandin series 1 (pge1). pge1 plays an important role in different tissues of the human body including modulation of immunity, anti-inflammatory, attenuation of prolactin high levels, and gastric mucosa protection.indications/ uses: premenstrual syndrome cyclical and non-cyclical mastalgia rheumatoid arthritis atopic dermatitis