Amlobenzamir 10/20mg hard gelatin 10caps

معلومات الدواء
الإسم التجاري Amlobenzamir 10/20mg hard gelatin 10caps -
الإسم العلمي Amlodipine+benazepril
السعر 16.00 جنيها
الشركات المنتجة Medizen pharmaceutical industries
Mira international
الوصف والإستخدام
وصف الدواء بالعربية
وصف الدواء بالإنجليزية Mechanism of action of amlodipineamlodipine is a second generation dihydropyridine ca channel blocker. it exerts it`s antihypertensive, antianginal actions through blocking the influx of ca ions through voltage gated l-type ca channels to the peripheral vascular smooth muscle cells, coronary smooth muscle cells and to the myocardial cells. thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .it markedly relax arterioles and milder effects on veins. they do not compromise haemodynamics and cerebral and renal perfusion.mechanism of action benazeprilat, the active metabolite of benazepril, competes with angiotensin i for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin i to angiotensin ii. inhibition of ace results in decreased plasma angiotensin ii. as angiotensin ii is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blo