Napibradine, (ivabradine), is a pure heart rate lowering agent, acting by selective and specific inhibition of the cardiac pacemaker If current that controls the spontaneous diastolic depolarisation in the sinus node and regulates heart rate.Napibradine, (ivabradine), is indicated for the symptomatic treatment of chronic stable angina pectoris in coronary artery disease adults with normal sinus rhythm.In adults unable to tolerate or with a contraindication to the use of beta-blockers.Or in combination with beta-blockers in patients inadequately controlled with an optimal beta-blocker dose and whose heart rate is lt 60 bpm.