Glucose use depends on metabolic rate. it is stored in the liver and muscle as glycogen.water use depends on clinical state of patient, body temperature and renal function. excreted through the skin, lungs, and kidneys. indications used as a source of energy particularly in total parenteral nutrition. dosage and administration the dose is dependent upon the age, weight, and clinical condition of the patient. however, for non-diabetics, the maximum infusion rate should be 4mg/kg/minute. at this rate the hepatic glucose production is minimized and peripheral glucose uptake maximized. should be administered through central vein as it can be irritating to the peripheral veins causing phlebitis.duration of action and excretionglucose use depends on metabolic rate. it is stored in the liver and muscle as glycogen.water use depends on clinical state of patient, body temperature and renal function. excreted through the skin, lungs, and kidneys.