About itopridedopamine(d2) antagonist, a prokinetic benzamide derivative, motility stimulant.mechanism of action of itoprideitopride has three way action. it inhibits the dopamine d2 receptor at the parasympathetic nerve ends.it increases the release of acetycholine and decreases the metabolism of acetylcholine by inhibiting the enzyme acetylcholinesterase (ache). by maintaining higher acetylcholine levels, itopride increases the oesophageal and gastrointestinal peristalsis, increases the lower oesophageal sphincter pressure, stimulates gastric motility, accelerates gastric emptying and improves gastro-duodenal coordination. itopride exerts anti-emetic actions because of its dopamine d2 receptor antagonistic action at ctz. interactions for itopridecisapride, atropine. typical dosage for itoprideadult-oral: 50 mg 3 times daily taken before each meal