Composition

Each 1 ml contains:
Neomycin (as sulphate) .......................

3.5 mg
Polymyxin B sulphate ...........................
16250 I.U.


Therapeutic Indications

Eye:
Treatment of superficial ocular infections caused by susceptible micro-organisms, such as conjunctivitis, keratitis, keratoconjunctivitis, corneal ulcers, blepharitis, and blepharoconjunctivitis.

Ear:
Bacterial infections in acute inflammation of the external ear and the auditory meatus (otitis externa), acute and chronic otitis media, post radical operations, and suppuration after tympanoplasty.


Dosage and Administration

Eye:
1-2 drops should be instilled into the affected eye(s) every 4 hours.
In severe infections, dosage may be increased to 2 drops every hour.

Ear:
Unless otherwise prescribed, 1-2 drops into the ear every 4 hours.

NEO-POL should be used only during one month after opening.


Contraindications

Hypersensitivity to the product.

Renal disease.

Patient with hearing disorders.


Warnings and Precautions

Prolonged therapy with NEO-POL , as with other antibiotics, may result in superinfection with nonsusceptible organisms, including fungi.

NEO-POL should be used with caution in:

Pregnancy.

Lactation.

Contact lenses should be removed prior to administration of NEO-POL.
Lenses may be reinserted 15 minutes following administration of the drug.

Patients should avoid allowing the tip of the dispensing container to contact the eye(s) or surrounding structures to avoid bacterial contamination.


Undesirable Effects

As with other antibiotics, sensitivity reactions such as transient irritation, burning, stinging, itching, swelling, and conjunctival erythema may occur in some patients.


Pharmacological Properties

NEO-POL is a combination of two bactericidal antibiotics, neomycin, an aminoglycoside antibiotic and polymyxin B, a bactericidal agent particularly effective against Pseudomonas aeruginosa.
Spectrum of activity includes the following pathogenic organsisms: Staphylococcus aureus, Haemophilus influenzae, Bordetella pertussis, Escherichia coli, Enterobacter and Klebsiella species, Neisseria species, and Pseudomonas aeruginosa.


Storage

Store at a temperature not exceeding 25°C.


Packaging

NEO-POL Sterile Eye/Ear Drops: 10 ml Plastic dropper bottle.