Dexapanthenol-containing creams have been widely used for treatment of lesions (superficial wounds) of the skin and mucous membranes. dexapanthenol is converted in tissues to pantothenic acid, a component of coenzyme a. coenzyme a catalyses early steps in the synthesis of fatty acids and sphingolipids which are of crucial importance for stratum corneum lipid bilayers and cell membrane integrity.