Composition

Each 1 ml contains :
Sodium cromoglycate ……….....................................................................
20 mg or 40 mg
Inactive ingredients:
EPICROM 2% Ophthalmic Drops (Sterile Solution): Benzalkonium chloride 0.01 %, edetate disodium, and purified water.

EPICROM 4% Ophthalmic Drops (Sterile Solution): Benzalkonium chloride 0.01 %, edetate disodium, and purified water.



Therapeutic Indications

Treatment of allergic ocular disorders including:
AlIergic conjunctivitis.

Giant papillary conjunctiviris.

Allergic keratoconjunctiviris.

Vernal keratitis.

Vernal keratoconjunctivitis.



Dosage and Administration

Symptomatic response to therapy (decreased itching, redness, watering and discharge) usuafly occurs within a few days, however treatment may be required for up to 6 weeks.

Adults, Adolescents and Children over 4 years of age:
Topical, to the conjunctiva.
1 drop 4-6 times a day at regular intervals.


Contraindications

Hypersensitivity to sodium cromoglycate or to any of the excipients.


Warnings and Precautions

EPICROM should be used in pregnancy only if cearIy needed.

Problems in breastfeeding have not been documented.


Undesirable Effects

Transient ocular stinging or burning upon instillation may occur, however it usually regresses with continued use.
Less frequently or rarely, dryness or puffiness around the eye, increased watering or itching of the eye, chemosis, eye irritation including styes not present before therapy may occur.


Pharmacological Properties

EPICROM is sodium cromoglycate, the mast cell stabilizer which inhibits mast cell release of histamine, leukotrienes, and other substances that cause hypersensitivity reactions.
probably by interfering with calcium transport across the mast cell membrane! It inhibits the degranulation of sensitized mast cells that occurs after exposure to specific antigens.



Packaging

EPICROM 2% Ophthalmic Drops: 10 ml Plastic dropper bottle.

EPICROM 4% Ophthalmic Drops: 10 ml Plastic dropper bottle.