Properties and Mechanism of Action:
Acni-Care (Erythromycin) reduces inflammatory lesions of acne vulgaris, presumably
due to its antibiotic action, but exact mechanism of its action is unknown.
Indications and Usage:
Acni-Care is indicated for the topical control of acne vulgaris.
Contraindications:
Acni-Care is contraindicated in persons who have shown hypersensitivity to
Erythromycin.
Precautions:
. Pregnancy:
Acni-Care should be used in pregnancy only if clearly needed.
. Nursing Mothers:
Caution should be exercised when Acni-Care is administered to nursing women.
Side Effects:
In rare cases skin dryness, tenderness, pruritus, erythema may occur
About erythromycinmacrolide antibiotic.mechanism of action of erythromycinerythromycin is a member of macrolide antibiotics. it binds to the 50s sub unit of bacterial ribosome and inhibits translocation.ie: they interfere with the transfer of the newly formed peptide chain from the a site to the p site and fails to expose the a site .so that a site is unable to bind with the next aminoacyl t rna complex. this leads to premature termination of amino acid chain and there by inhibits protein synthesis.indications for erythromycin1.tonsilitis 2.pharyngitis 3.pneumonia 4.diphtheria 5.pertusis 6.tetanus 7.sabe 8.syphilis 9.gonorrhea 10.wound and burn infection 11.rheumatic fever 12.acne 13.urogenital infection 14.chancroid 15.intestinal amoebiasis 16.skin and soft tissue infections 17.urethritis