About flumethasonetopical steroids, anti inflammatory and antipruritic drugsmechanism of action of flumethasoneits mechanism of action is to inhibit arachidonic acids role in the biosynthesis of prostaglandins and leukotrienes. flumethasone is active when it is not bound to the plasma protein transcortinindications for flumethasonetreatment of skin disorders (dermatitis,eczemia,psoriasis) inflammations of corticosteroid responsive dermatoses