Composition
Each tablet contains:
Xipamide ………….....................….
10 mg
Triamterene ………..................…..
30 mg

Therapeutic Indications
Mild to moderate hypertension.

Severe hypertension in combination with other antihypertensives.

All Kinds of oedema due to heart failure, kidney, liver or venous diseases.

Combination therapy with glycosides far treatment of congestive heart failure.

Dosage and Administration
Hypertension :
UnIess otherwise directed by the physician, 1 tablet daily, preferably after breakfast.

Oedema:
1-2 tablet(s) daily or every other day according to the severity of the disease.
If necessary, the dose may be increased to 3 tablets daily for a short period.

Contraindications
Hepatic coma.

Sulphonamide hypersensitivity.
Pregnancy and lactation.

Warnings and Precautions
Triamterene is not recommended in renal cases with creatinine cIearance < 10 ml/min.

Drug Interactions
The hypotensive effect can be augmented by other hypotensive drugs.

EPITENS can reduce the effect on blood sugar produced by antidiabetic drugs.

There is increased risk of hyperkalaemia if potssium salts, potassium sparing diuretics and ACE-inhibitors are added to EPITENS therapy.

Undesirable Effects
EPITENS is tolerated.
In some cases, it may cause mild gastrointestinal upset and mild vertigo