About lynestrenolsynthetic progestogen, hormonal contraceptionmechanism of action of lynestrenolas a synthetic oral progestogen, lynestrenol has similar effects as that of the natural progesterone hormone. it has a strong progestational effect on the uterine endometrium by transforming the proliferative endometrium into a secretory one. it also inhibits the secretion of gonadotropin, suppresses maturation of follicles in the ovaries and ovulation, and reduces menstrual bleeding. lynestrenol has minimal estrogenic, androgenic and anabolic effectsindications for lynestrenol1.contraception 2.menstrual disorder interactions for lynestrenolcarbamazepine, griseofulvin, phenobarbital, phenytoin and rifampicin: increased metabolism and subsequent reduction in efficacy of lynestrnol may increase plasma levels and toxicity of ciclosporin