Composition
Each 2 ml vial contains:
Dexamethasone sodium phosphate ....................................................... 4 mg/ml

Therapeutic Indications
Systemic administration:
EPIDRON injection is a potent, highly effective and versatile corticosteroid preparation which, being a true solution, may be administered intravenously as well as intramuscularly in the treatment of acute disorders responsive to corticosteroid therapy.
Local administration:
It may also be used as local therapy by intra-articular, intrabursal and soft-tissue injection.

Dosage and Administration
The appropriate dosage should be recommended by the physician.
Intravenous and Intramuscular injection:
The usual initial dose is 0.5 mg to 20 mg depending on the severity of the condition. The initial dose should be maintained or adjusted until adequate response is reached. Dosage requirements are variable and must be individualized on the basis of the disease under treatment and the response of the patient.
After initial improvement, single doses of 0.5 cc to 1 cc repeated as necessary may be sufficient. The total daily dosage usually need not exceed 20 cc (80 mg) even in severe conditions.

Contraindications
Systemic fungal infections.
Hypersensitivity to any component of this drug.

Warnings and Precautions
Corticosteroids may exacerbate systemic infections, including systemic fungal infections and tuberculosis, and should not be used unless they are needed to control drug reactions under medical supervision.
Use in Pregnancy and the Nursing mother:
Since adequate human reproduction studies have not been done with corticosteroids, the use of these drugs in pregnancy or in women of childbearing potential requires that the potential benefits of the drug be weighed against possible hazards to the mother, embryo or fetus.
Infants born by mothers who have received substantial doses of corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism.
Corticosteroids appear in breast milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other unwanted reactions, so, mothers taking pharmacological doses of corticosteroids should not nurse.

Undesirable Effects
Should side effects or any unusual feeling or symptom occur, a physician should be consulted immediately.

Packing
EPIDRON Injection: Box containing 2 ml vials