Composition
Each lyophilized ampoule contains:
Human Chorionic Gonadotrophin ........................
5000 I.U.

Each solvent ampoule contains:
Sodium chloride 0.9% ............................................
1 ml
Inactive ingredients: Lactose, dipotassium hydrogen phosphate, potassium dihydrogen phosphate.

Indications
Women:
Anovulatory infertility due to absent or low concentrations of gonadotrophins; to promote ovulation; where the cause of anovulation is not due to primary ovarian failure, and the women have been appropriately pre-treated with human menotrophins (Epigonal).

In combination with menotrophins as an adjunct to in-vitro fertilization procedures and other assisted conception techniques.

Men:
To stimulate and maintain spermatogenesis in men with hpogonadotrophic hypogonadism.

Dosage and Administration
The solvent should be added to the lyophilized powder; the reconstituted solution of Epifasi should be immediately administered by intramuscular injection only.
Any unused portion should be discarded.

Women:
Induction of ovulation and pregnancy: 5000-10000 units one day following the last dose of menotrophins (Epigonal).

Men:
Infertility: 5000 I.U.
is administered by intramuscular injection to stimulate spermatogenesis 3 times/week for 4-6 months before administration of menotrophins (Epigonal).

Contraindications
Hypersensitivity to the drug.

Precocious puberty.

Prostatic carcinoma or other androgen-dependent neoplasms.

Breast, uterine, ovarian, and testicular tumours.

Hypothalamus, pituitary, thyroid, and adrenal gland tumours.