Cromolyn sodium is indicated in the management of patients with mastocytosis. use of this product has been associated with improvement in diarrhea, flushing, headaches, vomiting, urticaria, abdominal pain, nausea, and itching in some patients.cromolyn sodium inhibits the release of mediators from sensitized mast cells. cromolyn sodium acts by inhibiting the release of histamine and leukotrienes (srs-a) from the mast cell.