Composition

Each vial contains:
Cephradine ……………...............................................................…………………………. 500 mg, 1 g
(As cephradine with L-arginine).
Each solvent ampoule contains:
Water for injection ………............................................................…………………………. 5 ml

Therapeutic Indications

CEPHRADINE is indicated for the treatment of infections of the urinary and respiratory tracts and of skin and soft tissues, these include:
Upper respiratory infections: pharyngitis, sinusitis, otitis media, tonsillitis, laryngo-tracheo bronchitis. Lower respiratory infections: acute and chronic bronchitis, lobar and bronchopneumonia. Urinary tract infections: cystitis, urethritis, pyelonephritis. Skin and soft tissuse infections: abscess, cellulitis, furunculosis, impetigo.
Cephradine has been shown to be effective in reducing the incidence of post-operative infections in patients undergoing surgical procedures associated with a high risk of infection, it is also of value where post-operative infections would be disastrous and where patients have a reduced host resistance to bacterial infection. Protection is best ensured by achieving adequate local tissue concentrations at the time contamination is likely to occur. Thus, CEPHRADINE should be administered immediately prior to surgery and treatment should be continued during the post-operative period.
Bacteriological studies to determine the causative organisms and their sensitivity to cephradine should be performed. Therapy may be instituted prior to receiving the results of the sensitivity test.
CEPHRADINE Parentral formulations:
For the treatment of:
Bone and joint infections. Septicaemia and endocarditis.
Sterile CEPHRADINE for injection is indicated primarily for those patients unable to tolerate oral medication. CEPHRADINE is also indicated for intravenous use either by direct injection or by intravenous infusion for the treatment of serious and life-threatening infections.