About buspironepsychotropic drug, serotonin 5-ht1a receptor partial agonist, weak dopamine (d2) antagonist azaspirodecanediones derivative, sedative, anxiolytic agent.mechanism of action of buspironebuspirone has a partial agonistic action on 5ht1a receptor and it stimulates presynaptic autoreceptors. this will produce a decrease in serotonin neuronal activity. it also has antagonistic action on post synaptic 5ht1a receptor. buspirone has a weak dopamine (d2) antagonistic action. mood elevation may be due to facilitation of noradrenergic system.indications for buspironeanxietytypical dosage for buspironeadult: 15 - 30 mg / day in 3 divided dose initial dose: 15 mg / day in 3 divided dose. dose can be gradually increased in every 3 days. maximum daily dose: 60 mg / day