Mechanismsclindamycin works by preventing bacteria from producing proteins that are essential to them. without these proteins the bacteria cannot grow, replicate and increase in numbers. the remaining bacteria eventually die or are destroyed by the immune system. this treats the infection.ssindication:sbacterial infections of the skin and soft tissue, such as infected ulcers, erysipelas, cellulitis.sbacterial infections of joints and bone (eg osteomyelitis).sbacterial infections of the abdominal cavity (peritonitis).sdental abscesses.streating falciparum malaria (unlicensed use).ssss