About ethamsylatesbenzenesulfonate derivative, systemic haemostatic.ssmechanism of action of ethamsylatesit exerts haemostatic action by acting on the first step of haemostasis by improving platelet adhesiveness and restoring capillary resistance. it decreases bleeding time and increases platelet aggregation. it reduces capillary bleeding when platelets are adequate. the drug exerts antihyaluronidase action and improves capillary wall stability. it inhibits pgi-2 synthesis and correct abnormal platelet function.ssindications for ethamsylatesused for prevention of haemorrhage in various conditions like :- s1. menorrhagia s2. metrorrhagia s3. after abortion s4. post partum haemorrhage s5. epistaxis s6. melena s7. haematuria s8. after tooth extraction s9. surgical procedures s10. haematemesis s11. haemoptysis