About isoxsuprinea beta-adrenergic agonist, tocolytic agent,peripheral vasodilator.mechanism of action of isoxsuprinethe drug exerts vasodilatory and smooth muscle relaxant action through acting as a beta adrenergic receptor agonist. it relaxes veins and arteries and causes dilatation and thus improves blood flow through them. it causes uterine relaxation due to it`s direct smooth muscle relaxant action.indications for isoxsuprine1. cerebral and peripheral vascular diseases 2. prevention of premature labour and threatened abortion. typical dosage for isoxsuprinecerebral and peripheral vascular diseases: oral: starts with 20mg- 6th hourly. reduces the dosage up to 10mg 8th hourly based on patient`s response. i.v.: initially at an infusion rate of 0.3mg/minute. then adjust the dosage based on the patient`s response. i.m.: initially 5mg 8th hourly and gradually increases to 10 to 20mg 8th hourly.