Composition
Each tablet contains:
Isosorbide dinitrate ............................................................................. 5 mg or 10 mg

Therapeutic Indications
Anginal syndromes.

Dosage and Administration
Sublingual route:
Place the tablet under the tongue and wait until complete dissolution.
Onset of action is rapid: approximately 2 minutes.
Anginal attack:
1-2 tablet(s) (Dinitra 5 mg Tablets) to be renewed if a new attack occurs.
Acute lung oedema:
Dinitra is associated with conventional treatment.
Give 1 or 2 tablet(s) (Dinitra 5 mg Tablets) to be renewed if necessary.
Oral route:
Tablets should be swallowed without chewing or sucking them.
Prevention of anginal attacks and heart failure of moderate severity:
2-4 tablets every 4-6 hours (Dinitra 5 mg Tablets), or 3-4 tablets daily (Dinitra 10 mg Tablets).
Treatment of refractory heart failure and of certain unstable types of angina with several painful attacks per day:
4-8 tablets of (Dinitra 10 mg Tablets) daily.

Contraindications
Hypersensitivity to the nitrate derivatives.

Undesirable Effects
At the beginning of treatment, headache or faintness with a tendency to vertigo may occur; in such a case the patient should lie down.

Pharmacological Properties
Dinitra has a vasodilating action on coronary vessels, producing a mild and prolonged increase in coronary blood flow and so a considerable improvement in the oxygen supply to the myocardium takes place.

Package
Dinitra 5 mg Tablets: Box containing 30 tablets or 1000 tablets.
Dinitra 10 mg Tablets: Box containing 60 tablets or 1000 tablets.