Indication for the treatment of mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and stable coronary disease.about amlodipinecalcium channel blocker, anti hypertensive,anti angina.mechanism of action of amlodipineamlodipine is a second generation dihydropyridine ca channel blocker. it exerts it`s antihypertensive, antianginal actions through blocking the influx of ca ions through voltage gated l-type ca channels to the peripheral vascular smooth muscle cells, coronary smooth muscle cells and to the myocardial cells. thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .it markedly relax arterioles and milder effects on veins. they do not compromise haemodynamics and cerebral and renal perfusion.indications :1.hypertension 2.prinzmetal`s angina 3.stable angina