Pharmacologynonspecific potassium channel blocker which improves conduction in focally demyelinated axons by delaying repolarization and prolonging the duration of action potentials. enhanced neuronal conduction is thought to strengthen skeletal muscle fiber twitch activity, thereby, improving peripheral motor neurologic function.indicationstreatment to improve walking in patients with multiple sclerosis (ms)dosing: adultmultiple sclerosis: oral: 10 mg every 12 hours (maximum daily dose: 20 mg)- no additional benefit seen with doses >20 mg daily