Serpass (sertraline), is a potent and specific inhibitor of neuronal serotonin (5-HT3) uptake in vitro, which results in the potentiation of the effects of 5-HT3 in animals. It has only very weak effects on norepinephrine and dopamine neuronal reuptake.Serpass (sertraline), is indicated for the treatment of: 1.Major depressive episodes. Prevention of recurrence of major depressive episodes.2.Panic disorder, with or without agoraphobia.3.Obsessive compulsive disorder (OCD) in adults and pediatric patients aged 6-17 years.4.Social anxiety disorder.5.Post-traumatic stress disorder (PTSD).