White tablets -2mg estradiol valeratepale brown tablets - 500 micrograms norgestrel + 2mg estradiol valerate.therapeutic indicationshormone replacement therapy (hrt) for oestrogen deficiency symptoms in perimenopausal and postmenopausal women.prevention of osteoporosis in postmenopausal women at high risk of future fractures who are intolerant of, or contraindicated for, other medicinal products approved for the prevention of osteoporosis.