About pinaverium bromidea calcium channel blocker, for functional gastrointestinal disorder.mechanism of action of pinaverium bromidepinaverium is a calcium channel blocker. it inhibits the calcium influx through voltage-dependent calcium channel in the intestinal smooth muscle and produces relaxation of smooth muscle.indications for pinaverium bromide1.irritable bowel syndrome 2.abdominal pain 3.bowel disturbances typical dosage for pinaverium bromideadult: oral:150mg/day in 3 divided doses. dose can be increased to 300mg/day if sufficient response is not obtained.