Indications s1.respiratory tract infection s2.urinary tract infection s3.bone and joint infection s4.skin infection s5.soft tissue infection ssdose:sadult: 250 - 500mg every 6 hours for 7 - 10 days.ssmechanism of action of ampicillinsampicillin is a bactericidal drug. it is a beta lactum antibiotic. it binds to the penicillin binding protein in the cell wall of bacteria and inhibits the enzyme transpeptidase which is responsible for the transpeptidation reaction in peptidoglycan synthesis. it also activates the endogenous enzyme which degrades the peptidoglycan.these results in inhibition of protein synthesis and there by cell wall synthesis. ampicillin is active against both gram positive and gram negative organism.