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Tetagam 250 iu – 1ml Human Tetanus Immunoglobulin
Tetagam is used to prevent tetanus infection (also known as lockjaw). Tetanus is a serious illness that causes convulsions (seizures) and severe muscle spasms that can be strong enough to cause bone fractures of the spine. Tetanus causes death in 30 to 40 percent of cases.

In recent years, two thirds of all tetanus cases have been in persons 50 years of age and older. A tetanus infection in the past does not make you immune to tetanus in the future.

Tetagam works by giving your body the antibodies it needs to protect it against tetanus infection. This is called passive protection. This passive protection lasts long enough to protect your body until your body can produce its own antibodies against tetanus.

Tetagam is to be administered only by or under the supervision of your doctor or other health care professional.

Passive, transient protection against tetanus in any person that may be contaminated with tetanus spores when: (1) patient’s personal history of immunization with tetanus toxoid is unknown or uncertain, (2) person received less than 2 prior doses of tetanus toxoid, or (3) person received 2 prior doses of tetanus toxoid, but delay of more than 24 h occurred between time of injury and initiation of tetanus prophylaxis.

Each vial also contains aminoacetic acid (as a stabilizer) 2.25% w/v, sodium chloride (as an isotonic agent), glacial acetic acid (pH adjustant), dried sodium carbonate, thimerosal (as a preservative) 0.01 w/v% and water for injection.

Tetagam is a sterile solution containing Tetagam which is prepared by Cohn fractionation from plasma of individuals with high titers of antibody to the tetanus antigen and heat inactivation step in manufacturing process (60°C, 10 hrs) is used to inactivate infectious agents eg, hepatitis B virus, hepatitis C virus, human immunodeficiency virus and others. All donor plasma used in preparation are tested that the results of anti-HIV 1/2, anti-HCV and HBsAg are negative.