About oxaliplatinalkylating-like- a diaminocyclohexane platinum analog, antineoplastic.mechanism of action of oxaliplatinoxaliplatin is a diaminocyclohexane platinum derivative with a broad spectrum of activity. it undergoes rapid non-enzymatic activation with the displacement of the oxalate ring by two chlorines.chloride is replaced by water and form a positively charged molecule. oxaliplatin is activated to a bis-aquated species through a number of reactions. the bis-aquated species then reacts with neighbouring guanine residues either on the same or neighbouring strands of dna. this leads to the cell death. its cytotoxic effects are more prominent at s phase but it kills the cells at all stages.