About lincomycinit is a macrolide.mechanism of action of lincomycinit binds to the 50s sub unit of bacterial ribosome and inhibits translocation.ie: they interfere with the transfer of the newly formed peptide chain from the a site to the p site and fails to expose the a site .so that a site is unable to bind with the next aminoacyl trna complex. this leads to premature termination of amino acid chain and there by inhibits protein synthesis indications for lincomycin1 intra abdominal abscess 2.lung abscess 3.acne 4.toxoplasmosis 5.peritonitis 6.endocarditis 7.malaria 8.empyema 9.skin and soft tissue infection