About loratadine
second generation h1 antagonist antihistamine.

mechanism of action of loratadine
loratadine blocks one type of receptor for histamine (the h1 receptor) and thus prevents activation (activation releasing other chemicals which produce the symptoms associated with allergy) of cells by histamine. drug also has mast cell stabilizing property.

indications for loratadine
1. allergic rhinitis (perennial and seasonal )
2. vasomotor rhinitis
3. allergic conjunctivitis
4. urticaria( mild uncomplicated )
5. angioedema
6. amelioration of allergic reactions to blood or plasma
7. dermatographism
8. adjunctive therapy in anaphylactic reactions
9. decongestant