This medication is used to treat hemorrhoids and itching/swelling in the rectum and anus. it is also used with other medications to treat certain intestinal problems (such as ulcerative colitis of the rectum and other rectal/anal inflammatory conditions). hydrocortisone suppositories help to relieve rectal pain itching bloody diarrhea and bleeding by reducing swelling (inflammation) directly in the rectum and anus. hydrocortisone belongs to a class of drugs called corticosteroids.

hydrocortisone acetate rect may interact with the following medications
severe interactions of hydrocortisone acetate rect:
these medications are not usually taken together.

immunosuppressives; immunomodulators

systemic corticosteroids/live vaccines
corticosteroids; corticotropin (acth)/amphotericin b
glucocorticoids/aldesleukin
corticosteroids/mifepristone
corticosteroids/selected anticholinesterase