Used to facilitate female conception, lutropin alfa performs the same actions as luteinizing hormone (lh), which is normally produced in the pituitary gland. lutropin is usually given in combination with follitropin alfa. together they stimulate the development of a follicle to prepare the reproductive tract for implementation and pregnancy. lutropin alfa also stimulates the theca cells to produce androgens and the secretion of estradiol by the follicles. lutropin alfa and follitropin alfa are discontinued once ultrasound assessment and serum estradiol concentrations show sufficient follicular maturation. hcg is then administered to complete follicular maturation and induce ovulation.indication: for treatment of infertility in women with hypothalamic or pituitary insufficiency (hypogonadotropic hypogonadism) and profound lh deficiency.