Indication and effect:taurolock™-hep500 is approved for instillation in all central venous access systems. taurolock™-hep500 remaining in the catheter prevents the formation of a bacterial biofilm. the catheter stays infection-free and works properly at high patency.composition:the lock solution contains (cyclo)-taurolidine, 500 units heparin per ml and citrate (4%). (cyclo)-taurolidine has a broad antimicrobial activity (incl. mrsa and vre) against gram-positive and gram-negative bacteria and fungi (e.g. candida).application:in application-free periods (e.g. between two dialysis sessions), taurolock™-hep500 is instilled into the saline-rinsed access system. the filling volume of the catheter/port system should be noted in this context.