Indications and usage:it is a hepatitis c virus (hcv) nucleotide analog ns5b polymerase inhibitor indicated for the treatment of chronic hepatitis c (chc) infection as a component of a combination antiviral treatment regimen.*efficacy has been established in subjects with hcv genotype 1, 4 , 5 or 6 infection.*dosage and administration:* one tablet taken once daily with or without food.* no need for ribavirin and interferon.