Retigabine or ezogabine is an anticonvulsant used as an adjunctive treatment for partial epilepsies in treatment-experienced adult patients.retigabine works primarily as a potassium channel opener
that is, by activating a certain family of voltage-gated potassium channels in the brain. this mechanism of action is unique among antiepileptic drugs, and may hold promise for the treatment of other neurologic conditions, including tinnitus, migraine and neuropathic pain.