Composition

Oxybin Tablets:
Each scored tablet contains:
Oxybutynin hydrochloride .................... 5 mg
Oxybin Syrup:
Each 5 ml syrup contains:
Oxybutynin hydrochloride..................... 5 mg
Inactive ingredients:
Oxybin Tablets: Microcrystalline cellulose, maize starch, sodium starch glycolate, magnesium stearate, lactose monohydrate, aerosil 200.
Oxybin Syrup:Citric acid anhydrous, sodium citrate anhydrous, sucrose, sorbitol 70 % solution, methylparaben, sucralose, sodium cyclamate, glycerol, purified water.

Therapeutic Indications

Oxybin is indicated for urinary incontinence, urgency and frequency in unstable bladder conditions due either to idiopathic detrusor instability or neurogenic bladder disorders (detrusor hyperreflexia) in conditions such as spina bifida and multiple sclerosis.
For children over 5 years of age, Oxybin may be used in nocturnal enuresis in conjunction with non-drug therapy where this alone, or in conjunction with other drug treatment, has failed.

Dosage and Administration

Adults:
The usual dose is 5 mg two or three times a day. This may be increased to a maximum dosage of 5 mg four times a day (20 mg) to obtain a satisfactory clinical response provided that the side effects are tolerated.
Children over 5 years of age:
Neurogenic bladder disorders:
The usual dose is 5 mg twice a day. This may be increased to a maximum of 5 mg three times a day to obtain a clinical response provided that the side effects are tolerated. Nocturnal enuresis:
The usual dose is 5 mg two or three times a day. The last dose should be given before bedtime.
In children, the maintenance dose may be achieved by upward titration from an initial dose of 2.5 mg twice daily.
Children under 5 years of age:
Not recommended.
Elderly:
The elimination half-life may be increased in some elderly patients, therefore, dosage should be individually titrated commencing at 2.5 mg 2-3 times a day. The final dosage will depend on response and tolerance to side effects. As with other anticholinergic drugs caution should be observed in frail and elderly patients.