Difluprednate is a corticosteroid, it is chemically a butyrate ester of 6(alpha),9(alpha)-difluoro prednisolone acetate. accordingly, difluprednate is sometimes abbreviated dfba, for difluoroprednisolone butyrate acetate.difluprednate emulsion is used for:treating swelling, pain, redness, or irritation of the eye after eye surgery. it is also used to treat uveitis (inflammation of the eye).difluprednate emulsion is an ophthalmic corticosteroid. it decreases inflammation (eg, pain, redness, swelling, warmth) of the eye.