About loxoprofen sodiumnsaid, propionic acid derivative, antiinflammatory and antipyretic propertymechanism of action of loxoprofen sodiumloxoprofen is a non-selective cyclooxygenase inhibitor. it works by reducing the synthesis of prostaglandins from arachidonic acid. it is a prodrug that is rapidly converted to its active metabolite after oral admin.indications for loxoprofen sodiumpain and inflammation associated with musculoskeletal and joint disordersinteractions for loxoprofen sodiumpossible increased risk of seizures when used with ciprofloxacin and norfloxacin may also increase serum levels of warfarin, methotrexate, lithium salts and sulphonylurea derivatives