About diclofenac (eye prep.)nsaid, ophthalmic sterile, topical anti-inflammatory ,analgesic.mechanism of action of diclofenac (eye prep.)diclofenac possess analgesic, anti-inflammatory and antipyretic action. it inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of prostaglandins (((pgs))). it is more potent against cyclo-oxygenase-2 enzyme as compared to other nsaids like indomethacin, naproxen etc. it reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake