About ibuprofensnsaid, a propionic acid derivative, analgesic and anti-inflammatory.ssmechanism of action of ibuprofensibuprofen has analgesic, anti-inflammatory and antipyretic action. it acts by inhibiting prostaglandin (pgs) synthesis and their release at the site of injury. prostaglandins cause tenderness and amplify the action of other algesics. ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. it also inhibits platelet aggregation and prolongs bleeding time.ssindications for ibuprofens1.rheumatoid arthritis s2.ankylosing spondylitis s3.acute gout s4.joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints s5.osteoarthritis s6.for the relief of fever, pain and inflammation in dental, minor surgery and orthopedic s7.dysmenorrhoea s8.juvenile arthritis s9.migraine s10.patent ductus arteriosus(iv)