About felodipinea selective calcium channel blocker, dihydropyridine derivative, anti hypertensive.mechanism of action of felodipinefelodipine is a vasoselective long acting dihydropyridine ca channel blocker. it exerts antihypertensive, antianginal actions through blocking the influx of ca2+ ions through voltage gated l-type ca channels to the peripheral vascular smooth muscle cells, coronary smooth muscle cells and to the myocardial cells. thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .it has smooth muscle relaxant action produces by release of nitric oxide from endothelium and thus inhibit cyclic amp-phosphodiesterase resulting in raised cyclic amp in smooth muscle. nitric oxide exerts anti atherosclerotic action.