Insulin degludec is an ultralong-acting basal insulin analogue. it is administered via subcutaneous injection once daily to help control the blood sugar level of those with diabetes. it has a duration of action that lasts up to 42 hours (compared to 18 to 26 hours provided by other marketed long-acting insulins such as insulin glargine and insulin detemir), making it a once-daily basal insulin, that is one that provides a base insulin level, as opposed to the fast and short acting bolus insulins.insulin degludec is a modified insulin that has one single amino acid deleted in comparison to human insulin, and is conjugated to hexadecanedioic acid via gamma-l-glutamyl spacer at the amino acid lysine at position b29.