Bisocard (bisoprolol hemifumarate), a highly beta1-selective beta-adrenoceptor antagonist with low beta2-receptor affinity, is taken as once daily for 24-hour control of the diseases. It is indicated in the management of mild to moderate hypertension (high blood pressure), angina pectoris and CHF (congestive heart failure).


About bisoprololbeta1-selective adrenergic blocker, antihypertensive.mechanism of action of bisoprololbisoprolol is a cardio selective beta-1 adrenergic antagonist.it has negative chronotropic and negative inotropic effects on heart. it decreases oxygen consumption- cardiac work and aortic pressure. it decreases central sympathetic out flow and also decreases nor adrenaline and renin releases. the drug decreases bp in hypertensive individuals. indications for bisoprolol1.hypertension 2.coronary artery diseases contra-indications of bisoprolol1.hypersensitivity to the drug 2.second or third degree heart block 3.congestive heart failure 4.cardiogenic shock 5.sinus bradycardia 6.chronic obstructive pulmonary diseases 7.bronchial asthma 9.peripheral arteriolar disorders 10.renal impairment.