Levocetirizinesa third-generation non-sedative h1 antagonist, antihistamine.ssmechanism of action of levocetirizinesthis active enantiomer of cetrizine is a potent, nonsedative and selective h1 receptor antagonist.
it antagonizes the allergic symptoms produced by histamines like runny nose, cold, cough etc.
it also inhibit eotaxin-induced eosinophil tem through both dermal and lung micro vascular endothelial cells.
so inhibit eosinophil chemotaxis and also inflammation caused by it.ssindications for levocetirizines

1.
rhinitis (seasonal and perennial) s

2.
idiopathic urticaria sinteractions for levocetirizinescoadministration with alcohol or other cns depressants may have additional cns depressant effect.