About pregabalina gaba agonist, anticonvulsant.mechanism of action of pregabalinspregabalin is a gaba neurotransmitter analog. it produces its action by modulating calcium channels and also reduces the release of neurotransmitters such as glutamate, norepinephrine, serotonin, dopamine and substance p.indications for pregabalin1.epilepsy 2.generalised anxiety disorder s3.neuropathic pain stypical dosage for pregabalins150- 300mg / day in 2 divided doses