Composition
Each Sustained Release (S.R.) tablet contains:
Diltiazem hydrochloride ................................................................................ 90 mg or 180 mg

Therapeutic Indications
Chronic stable angina pectoris (classic effort-associated angina).
Prinzmetal's (variant) angina.
Mild and moderate hypertension.

Dosage and Administration
The usual initial dose is 90 mg twice daily, with or without food.
Dosage may be increased gradually to 180 mg twice daily if required.

Contraindications
Hypersensitivity to the product.
Pregnancy.
Sick sinus syndrome.
Pre-existing second- or third-degree atrioventricular block.
Hypotension (systolic blood pressure below 90 mmHg).
Acute myocardial infarction.
Pulmonary congestion (documented by X-ray).
Decompensated cardiac failure.
Severe bradycardia (below 50 bpm).
Acute porphyria.

Warnings and Precautions
DILTIAZEM S.R. should be used with caution in:
Bradycardia.
Patients with first degree AV block or prolonged PR interval.
Impaired liver or kidney function.
Elderly patients.

Breast-feeding should be discontinued during drug use.
In children, safety of the drug has not been established.
Sudden withdrawal of DILTIAZEM S.R. should be avoided