Shorsalin (oxcarbazepine), is structurally a derivative of carbamazepine, adding an extra oxygen atom to the benzyl carboxamide group. It is partial seizures in epileptic children and adults. Shorsalin (oxcarbazepine), is indicated for the treatment of partial seizures with or without secondarily generalised tonic-clonic seizures. Also used as monotherapy or adjunctive therapy in adults and in children of 6 years of age and above.


About oxcarbazepinecarboxamide derivative,iminostilbenes, anticonvulsant, mood stabilizing agent.mechanism of action of oxcarbazepineoxcarbazepine prolongs the inactivated state of voltage sensitive neuronal sodium ion channel either by increasing the efflux or by decreasing the influx of sodium ion across the cell membrane and inhibits the high frequency discharge. it blocks the repetitive impulses that trigger seizures and it stabilizes the neuronal membrane. in addition it increases the potassium conductance and modulates the high voltage activated calcium channels. these also produce anticonvulsant effect. indications for oxcarbazepine1. treatment of partial seizureinteractions for oxcarbazepinephenytoin: oxcarbazepine with phenytoin / phenobarbitol can increase their levels by 40% / 15%. oral contraceptive: efficacy of oral contraceptives, specially those containing ethinyl estradiol & levonorgestrol, can be reduced.